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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLK1 All Species: 11.52
Human Site: S172 Identified Species: 23.03
UniProt: O15075 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15075 NP_004725.1 740 82224 S172 S L A T A K G S P S E V R E N
Chimpanzee Pan troglodytes XP_522657 872 96662 S315 S L A T A K G S P S E V R E N
Rhesus Macaque Macaca mulatta XP_001082020 783 85228 V187 A S S V K S E V K E S K D F I
Dog Lupus familis XP_849124 740 82175 S172 S L A T A K G S P S E V R E N
Cat Felis silvestris
Mouse Mus musculus Q9JLM8 756 84135 G172 S L A T A K G G P S E V R E N
Rat Rattus norvegicus Q5MPA9 767 83998 K187 A S A K S E V K E S K D F I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511397 792 88039 G233 S L A T A K G G P S D V R E N
Chicken Gallus gallus XP_417099 1048 115422 G478 S L A T A K G G T P D T K E N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q501V0 422 47914
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7PLI7 748 82953 Y170 Y R N G D R F Y P G I T I P V
Honey Bee Apis mellifera XP_394386 670 74883 S143 I F K K V E Y S S T K V R R G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189418 661 74296 D135 S Y V C S S Q D V F K R M E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 65.3 99.8 N.A. 96.4 65.3 N.A. 86.2 63.7 N.A. 24.7 N.A. 29.8 41 N.A. 52.3
Protein Similarity: 100 80.1 77.5 99.8 N.A. 97.3 77.8 N.A. 88 64.9 N.A. 35 N.A. 47.5 57.9 N.A. 65.9
P-Site Identity: 100 100 0 100 N.A. 93.3 13.3 N.A. 86.6 60 N.A. 0 N.A. 6.6 20 N.A. 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 40 N.A. 93.3 73.3 N.A. 0 N.A. 13.3 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 59 0 50 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 9 0 0 17 9 9 0 0 % D
% Glu: 0 0 0 0 0 17 9 0 9 9 34 0 0 59 0 % E
% Phe: 0 9 0 0 0 0 9 0 0 9 0 0 9 9 0 % F
% Gly: 0 0 0 9 0 0 50 25 0 9 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 0 9 9 9 % I
% Lys: 0 0 9 17 9 50 0 9 9 0 25 9 9 0 9 % K
% Leu: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 50 % N
% Pro: 0 0 0 0 0 0 0 0 50 9 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 9 0 0 0 0 0 9 50 9 0 % R
% Ser: 59 17 9 0 17 17 0 34 9 50 9 0 0 0 0 % S
% Thr: 0 0 0 50 0 0 0 0 9 9 0 17 0 0 0 % T
% Val: 0 0 9 9 9 0 9 9 9 0 0 50 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 0 9 9 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _